OPAL Plus

Algorithm Computation

Enter a single Protein Sequence Click here to add sample protein sequence

Upload HMM Alignment File (Click here to download sample file)

Upload hsa2 File (Click here to download sample file)

Upload hsb2 File (Click here to download sample file)

Upload spd3 File (Click here to download sample file)

Enter Email Address (optional)

Submit Job

Dowload Results

View Output

References

Sharma, R., Sharma, A., Raicar, G., Tsunoda, T., and Patil, A., OPAL+: Length-specific MoRF prediction in intrinsically disordered protein sequences, 2018

Sharma, R., Raicar, G., Tsunoda, T., Patil, A., and Sharma, A., OPAL: prediction of MoRF regions in intrinsically disordered protein sequence, Bioinformatics, vol. 34, no. 11, pp. 1850-1858, 2018. Webserver

Sharma, R., Bayarjargal, M., Tsunoda, T., Patil, A. and Sharma, A., MoRFPred-plus: Computational Identification of MoRFs in Protein Sequence using physicochemical properties and HMM profiles, Journal of Theoretical Biology, vol. 437, pp. 9-16, 2018

Malhis N, and Gsponer J. Computational Identification of MoRFs in Protein Sequences. Bioinformatics (2015) 31 (11): 1738-1744

Notes

Procedure for producing the HMM Alignment File

Procedure to produce hsa2, hsb2, spd3 files using SPIDER2 server

Locally running OPAL program